Gut Health: Part 2

Part 2: Probiotics and Prebiotics in Gut Health

For background info, please refer to Gut Health, Part 1: Why we should focus on the health of our gut this January and NOT our weight.  
(Essential Jo: Click to See my blog post of 6th Jan 2017)

In the second part of this gut health series, we are going to look at the role of probiotics and prebiotics in gut health – possibly one of the most exciting new topics to emerge in nutrition in the last few years. If you missed Part 1: Why we should focus on the health of our gut do take a look at it first to give you a little more background.  
(Essential Jo: Click to See my blog post of 6th Jan 2017)

What are probiotics?

Probiotics are “live micro-organisms, which when consumed in adequate amounts, confer a health effect on the host”. Use of probiotic foods is an ancient tradition – even as far back as the time of Genghis Khan, fermented milk was being drunk as an elixir of strength and health.


Most often, probiotic foods or supplements contain strains of either Lactobacillus or Bifidobacterium bacteria, usually from fermented dairy products. However, before starting to act, they have to survive the hazardous journey to reach our gut:

They need to first get through manufacturing, transportation and storage processes, to reach our shopping bags alive and in good condition.
Then they must make it through the acidic environment of our stomach (designed precisely to kill off any wayward bacteria) and through the swamp of potent digestive juices and enzymes secreted by the gallbladder and pancreas.
Finally, if they succeed in reaching their destination, the large bowel, they then actually need do some good for the host rather than just going along for a free ride, or even possibly doing some untoward harm.
Because of these difficulties with getting the right probiotics to the right place, it is important to point out that the benefits which are seen in clinical trials may not all be possible to achieve with the yoghurts, tablets or other supplements available over-the-counter.

Despite all these challenges, however, good quality strains of probiotics have been associated with beneficial effects in some disease processes. The best evidence base for them so far is with antibiotic-associated diarrhoea, but researchers are examining a huge range of other conditions, from cancer to eczema – even mental health – which may benefit from probiotics (Tuohy et al., 2003) (NHS Choices, 2015).

Limitations
Most of the clinical research that has been carried out on prebiotics has been in unwell populations, and even then they are not yet in widespread use. We do not yet know much about the impact that taking probiotics might have in generally healthy people (Puupponen-Pimia et al., 2002). Anecdotally I have found them to be of tremendous benefit for myself and some of my clients – I am always cautious to recommend any supplements on this sort of platform, but when I do use and prescribe probiotics, I go for the very highest quality.

Probiotics, even as tablets, are also still regarded as foods. Therefore they do not have to undergo the same rigorous testing as medicines do, so it is difficult to know if they actually contain the bacteria they claim, alive, in an adequate dose, and are able to give you a tangible benefit (NHS choices, 2015). The European Food Safety Authority has even gone so far as to ban the probiotic food industry from certain advertising claims, such as that they ‘boost the immune system’, because there is insufficient evidence to back such claims up at the moment. A healthy dose of skepticism is often helpful in nutritional science!

As Dr Alessio Fasano so neatly puts it, we can compare our current knowledge of the microbiota to our knowledge of space. We know the universe exists (our microbiota), and we are getting to grips with the fact the Milky Way is there (the major strains of bacteria), but we are far off knowing where London is! In other words, there is a lot of detail still to understand before we are able to fully utilize probiotics for health. Do take a look at some of Dr Fasano’s YouTube talks if you are interested – he makes the gut a really fascinating and understandable topic!



What about prebiotics – are they the same thing?

No. Prebiotics are a class of nutrients called ‘oligosaccharides’ (a type of fibre) which pass through the upper portion of the gut undigested, to feed and stimulate the growth of microbes further down. I think about it as nectar for gut bugs!

Types of prebiotic that are known to alter the microbiota include (Tuohy et al., 2003);

Inulin & Fructooligosaccharides – found in foods such as Jerusalem artichoke, asparagus, leeks, green bananas, chicory and onions (Sabater-Molina et al., 2009)
Lactulose
Galactooligosaccharides – found naturally in breast milk to help feed the microbiota of new born babies.

In general, a dose of more than 20g a day of all of these combined, may lead to unwanted side effects such as flatulence and bloating (Tuohy et al., 2003). Especially if you suffer from IBS, I would suggest it is a sensible idea to ‘start low and go slow’ on introducing these to your diet.

As an added benefit, when our gut microbes break down these prebiotic fibres, especially inulin, they release a compound called butyric acid (Scott et al., 2013). This is especially important in gut health, as not only is in anti-inflammatory, but it also helps build up the gut defence barrier and decreases oxidative stress. All really useful effects. Plus it might even help to signal to our brain that we are full and satisfied at the end of a meal (Hamer et al., 2007).

My pragmatic approach, if you are generally well, and would like to boost your probiotic and prebiotic intake, is to use functional foods wherever possible. 
In Part 3: How to nourish your gut health, we will explore lots of ideas on how to do this.

Images and Article - Source